4-(4-Chlorophenyl)piperidin-4-ol
Identifieur interne : 002653 ( Main/Exploration ); précédent : 002652; suivant : 0026544-(4-Chlorophenyl)piperidin-4-ol
Auteurs : Grzegorz Dutkiewicz [Pologne] ; B. P. Siddaraju [Inde] ; H. S. Yathirajan [Inde] ; M. S. Siddegowda [Inde] ; Maciej Kubicki [Pologne]Source :
- Acta Crystallographica Section E: Structure Reports Online [ 1600-5368 ] ; 2010.
Abstract
In the title compound, C11H14ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the molecules are linked into a centrosymmetric tetramer through strong O—H⋯N and weak N—H⋯O hydrogen bonds; the N and O atoms act as both donor and acceptor for these interactions. The tetramers are further joined by hydrogen bonds into a layer parallel to (100).
Url:
DOI: 10.1107/S1600536810004216
PubMed: 21580330
PubMed Central: 2983646
Affiliations:
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Le document en format XML
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P." last="Siddaraju">B. P. Siddaraju</name><affiliation wicri:level="1"><nlm:aff id="b">Department of Chemistry, V. V. Puram College of Science, Bangalore 560 004,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Yathirajan, H S" sort="Yathirajan, H S" uniqKey="Yathirajan H" first="H. S." last="Yathirajan">H. S. Yathirajan</name><affiliation wicri:level="1"><nlm:aff id="c">Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570 006,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Siddegowda, M S" sort="Siddegowda, M S" uniqKey="Siddegowda M" first="M. S." last="Siddegowda">M. S. Siddegowda</name><affiliation wicri:level="1"><nlm:aff id="c">Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570 006,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kubicki, Maciej" sort="Kubicki, Maciej" uniqKey="Kubicki M" first="Maciej" last="Kubicki">Maciej Kubicki</name><affiliation wicri:level="1"><nlm:aff id="a">Department of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, 60-780 Poznań,<country>Poland</country></nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Acta Crystallographica Section E: Structure Reports Online</title><idno type="eISSN">1600-5368</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In the title compound, C<sub>11</sub>H<sub>14</sub>ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the molecules are linked into a centrosymmetric tetramer through strong O—H⋯N and weak N—H⋯O hydrogen bonds; the N and O atoms act as both donor and acceptor for these interactions. 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